Highly Purified Conjugates of Natural Chlorin with Cobalt Bis(dicarbollide) Nanoclusters for PDT and BNCT Therapy of Cancer

Highly Purified Conjugates of Natural Chlorin with Cobalt Bis(dicarbollide) Nanoclusters for PDT and BNCT Therapy of Cancer

To combine the neutron-capturing and photodynamic properties of boron nanoclusters and derivatives of natural chlorins, respectively, in one molecule, conjugate of chlorin e6 methyl ester with cyclen and dioxane and nitrile derivatives of cobalt bis(dicarbollide) were synthesized. The conditions for...

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Bibliographic Details
Main Authors: Maria K. Fedotova, Maksim N. Usachev, Ekaterina V. Bogdanova, Ekaterina Diachkova, Yuriy Vasil’ev, Vladimir I. Bregadze, Andrey F. Mironov, Mikhail A. Grin
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Bioengineering
Subjects:
anticancer
boron neutron capture therapy
nanoconjugate
neutron sensitizer
photodynamic therapy
photosensitizer
Online Access:https://www.mdpi.com/2306-5354/9/1/5

Internet

https://www.mdpi.com/2306-5354/9/1/5

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