Comparing cell‐free circulating tumor DNA mutational profiles of disease‐free and nonresponders patients with oropharyngeal squamous cell carcinoma

Comparing cell‐free circulating tumor DNA mutational profiles of disease‐free and nonresponders patients with oropharyngeal squamous cell carcinoma

Abstract Objective The purpose of this study was to investigate whether somatic nonsynonymous variants in tumor tissue can potentially be identified in circulating cell‐free DNA (cfDNA) of head and neck oropharyngeal squamous cell carcinoma (OPSCC) patients using next‐generation sequencing and can p...

Full description

Bibliographic Details
Main Authors: Alok R. Khandelwal, Adam H. Greer, Mickie Hamiter, Janmaris Marin Fermin, Thomas McMullen, Tara Moore‐Medlin, Glenn Mills, Jose M. Flores, Hong Yin, Cherie‐Ann O. Nathan
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Laryngoscope Investigative Otolaryngology
Subjects:
cfDNA
oropharynx
recurrence
TP53
Online Access:https://doi.org/10.1002/lio2.447

Internet

https://doi.org/10.1002/lio2.447

Similar Items