Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli
Kidney intercalated cells are involved in acid-base homeostasis in the kidneys. Here, the authors use single cell transcriptomics and find that interalated cells exhibit a transcriptional response conducive to defense and can engulf and acidify internalized bacteria, similarly to professional phagoc...
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Bibliographic Details
| Main Authors: |
Vijay Saxena,
Hongyu Gao,
Samuel Arregui,
Amy Zollman,
Malgorzata Maria Kamocka,
Xiaoling Xuei,
Patrick McGuire,
Michael Hutchens,
Takashi Hato,
David S. Hains,
Andrew L. Schwaderer |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-22672-5
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