Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting

Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting

Summary: Spatial regulation of angiogenesis is important for the generation of functional engineered vasculature in regenerative medicine. The Notch ligands Jag1 and Dll4 show distinct expression patterns in endothelial cells and, respectively, promote and inhibit endothelial sprouting. Therefore, p...

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Bibliographic Details
Main Authors: Laura A. Tiemeijer, Tommaso Ristori, Oscar M.J. A. Stassen, Jaakko J. Ahlberg, Jonne J.J. de Bijl, Christopher S. Chen, Katie Bentley, Carlijn V.C. Bouten, Cecilia M. Sahlgren
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Bioengineering
Biological sciences
Developmental biology
Tissue engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222005764

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222005764

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