Cellular Immune Responses in Islet Xenograft Rejection

Cellular Immune Responses in Islet Xenograft Rejection

Porcine islets surviving the acute injury caused by humoral rejection and IBMIR will be subjected to cellular xenograft rejection, which is predominately mediated by CD4+ T cells and is characterised by significant infiltration of macrophages, B cells and T cells (CD4+ and CD8+). Overall, the respon...

Full description

Bibliographic Details
Main Authors: Min Hu, Wayne J. Hawthorne, Shounan Yi, Philip J. O’Connell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
xenograft
islet (cell) transplantation
T cell
macrophage cell
transgenic pig
IBMIR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.893985/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.893985/full

Similar Items