A semi-automated method for unbiased alveolar morphometry: Validation in a bronchopulmonary dysplasia model.

Reproducible and unbiased methods to quantify alveolar structure are important for research on many lung diseases. However, manually estimating alveolar structure through stereology is time consuming and inter-observer variability is high. The objective of this work was to develop and validate a fas...

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Bibliographic Details
Main Authors: Thomas Salaets, Bieke Tack, André Gie, Benjamin Pavie, Nikhil Sindhwani, Julio Jimenez, Yannick Regin, Karel Allegaert, Jan Deprest, Jaan Toelen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0239562