Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p

By identifying circ-CREBBP out of differently expressed circRNAs in seminal plasma extracellular vesicles from boars with high and low sperm motility, the circRNA is shown to play a role in sperm survival and apoptosis.

Bibliographic Details
Main Authors: Ning Ding, Yu Zhang, Mengna Huang, Jianfeng Liu, Chonglong Wang, Chun Zhang, Jinkang Cao, Qin Zhang, Li Jiang
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04263-2