Transient temperature fluctuations severely decrease P. falciparum susceptibility to artemisinin in vitro
Clinical studies suggest that outcomes for hospitalised malaria patients can be improved by managed hypothermia during treatment. We examined the impact of short pulses of low temperature on ring-stage susceptibility of Plasmodium falciparum to artemisinin in vitro. The usually artemisinin-sensitive...
Main Authors: | Ryan C. Henrici, Donelly A. van Schalkwyk, Colin J. Sutherland |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-04-01
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Series: | International Journal for Parasitology: Drugs and Drug Resistance |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211320718301167 |
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