Estrogen exacerbates the nociceptive effects of peripheral serotonin on rat trigeminal sensory neurons
Orofacial pain disorders involving trigeminal sensory neurons disproportionately affect women and can be modulated by hormones, especially estrogen (E2). Proinflammatory mediators, like serotonin (5HT), can act on sensory neurons expressing the transient receptor potential vanilloid 1 (TRPV1) ion ch...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
|
Series: | Neurobiology of Pain |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452073X21000143 |