Identifying causal genes for migraine by integrating the proteome and transcriptome

Identifying causal genes for migraine by integrating the proteome and transcriptome

Abstract Background While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack of evidence about how these variants contribute to the development of migraine. We employed an integrative pipeline to efficiently transform genetic associat...

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Bibliographic Details
Main Authors: Shuang-jie Li, Jing-jing Shi, Cheng-yuan Mao, Chan Zhang, Ya-fang Xu, Yu Fan, Zheng-wei Hu, Wen-kai Yu, Xiao-yan Hao, Meng-jie Li, Jia-di Li, Dong-rui Ma, Meng-nan Guo, Chun-yan Zuo, Yuan-yuan Liang, Yu-ming Xu, Jun Wu, Shi-lei Sun, Yong-gang Wang, Chang-he Shi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:The Journal of Headache and Pain
Subjects:
Migraine
Transcriptome-wide association study
Proteome-wide association studies
Fine-mapping
Online Access:https://doi.org/10.1186/s10194-023-01649-3

Internet

https://doi.org/10.1186/s10194-023-01649-3

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