Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles
Background Trans-acting programmed death-ligand 1 (PD-L1) derives from malignant cells in three known forms. High levels of secreted splice variant PD-L1 (sPD-L1), ADAM10/ADAM17-shed sPD-L1, and PD-L1-positive extracellular vesicles (evPD-L1) each predict poor prognosis and limited response to PD-(L...
मुख्य लेखकों: | , , , , , , , , , , , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
BMJ Publishing Group
2020-10-01
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श्रृंखला: | Journal for ImmunoTherapy of Cancer |
ऑनलाइन पहुंच: | https://jitc.bmj.com/content/8/2/e001113.full |