The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
Three p160 family members, p/CIP, SRC1, and TIF2, have been identified as transcriptional coactivators for nuclear hormone receptors and other transcription factors in vitro. In a previous study, we reported initial characterization of the obesity-resistant phenotypes of p/CIP and SRC-1 double knock...
Main Authors: | Zhiyong Wang, O Jameel Shah, Tony Hunter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3409189?pdf=render |
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