Bactericidal Synergism between Phage YC#06 and Antibiotics: a Combination Strategy to Target Multidrug-Resistant Acinetobacter baumannii In Vitro and In Vivo

Bactericidal Synergism between Phage YC#06 and Antibiotics: a Combination Strategy to Target Multidrug-Resistant Acinetobacter baumannii In Vitro and In Vivo

ABSTRACT Phage-antibiotic combination (PAC) therapy is a potential new alternative to treat infections caused by pathogenic bacteria, particularly those caused by antibiotic-resistant bacteria. In the present study, phage YC#06 against highly multidrug-resistant Acinetobacter baumannii 4015 was isol...

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Bibliographic Details
Main Authors: Jun Luo, Libo Xie, Min Liu, Qianyuan Li, Peng Wang, Chunhua Luo
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
phage-antibiotic combinations
in vitro
in vivo
multidrug-resistant A. baumannii
phage-antibiotic synergy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00096-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00096-22

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