Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients

Abstract Background The purpose of this work was to investigate noninvasive early detection of treatment response of breast cancer patients to neoadjuvant chemotherapy (NAC) using chemical exchange saturation transfer (CEST) measurements sensitive to amide proton transfer (APT) at 7 T. Methods CEST...

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Bibliographic Details
Main Authors: Erwin Krikken, Vitaliy Khlebnikov, Moritz Zaiss, Rajni A. Jibodh, Paul J. van Diest, Peter R. Luijten, Dennis W. J. Klomp, Hanneke W. M. van Laarhoven, Jannie P. Wijnen
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-018-0982-2