<i>PADI4</i> Haplotypes Contribute to mRNA Expression, the Enzymatic Activity of Peptidyl Arginine Deaminase and Rheumatoid Arthritis Risk in Patients from Western Mexico

<i>PADI4</i> Haplotypes Contribute to mRNA Expression, the Enzymatic Activity of Peptidyl Arginine Deaminase and Rheumatoid Arthritis Risk in Patients from Western Mexico

Citrullination is catalyzed by the peptidyl arginine deiminase 4 (PAD4) enzyme, encoded by the <i>PADI4</i> gene. Increased PAD4 activity promotes the onset and progression of rheumatoid arthritis (RA). This study aimed to evaluate the association of <i>PADI4</i> haplotypes w...

Full description

Bibliographic Details
Main Authors: Mónica Guadalupe Matuz-Flores, Jesús Alfredo Rosas-Rodríguez, Orlando Tortoledo-Ortiz, Salvador Muñoz-Barrios, Gloria Esther Martínez-Bonilla, Jorge Hernández-Bello, Christian Johana Baños-Hernández, Cesar Pacheco-Tena, Gabriela Athziri Sánchez-Zuno, Beatriz Panduro-Espinoza, José Francisco Muñoz-Valle
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Current Issues in Molecular Biology
Subjects:
ACPA
<i>PADI4</i> gene
<i>PADI4</i> expression
PAD4 activity
Rheumatoid arthritis
Online Access:https://www.mdpi.com/1467-3045/44/9/293

Internet

https://www.mdpi.com/1467-3045/44/9/293

Similar Items