SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization

SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization

The function of SLC7A11 in the process of ferroptosis is well-established, as it regulates the synthesis of glutathione (GSH), thereby influencing tumor development along with drug resistance in non-small cell lung cancer (NSCLC). However, the determinants governing SLC7A11's membrane trafficki...

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Bibliographic Details
Main Authors: Jun Deng, Xu Lin, Jiajia Qin, Qi Li, Yingqiong Zhang, Qingyi Zhang, Cong Ji, Shuying Shen, Yangling Li, Bo Zhang, Nengming Lin
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Redox Biology
Subjects:
SPTBN2
Ferroptosis
NSCLC
SLC7A11
membrane trafficking
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000156

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http://www.sciencedirect.com/science/article/pii/S2213231724000156

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