The conserved single-cleavage mechanism of animal DROSHA enzymes

Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.

Bibliographic Details
Main Authors: Thuy Linh Nguyen, Trung Duc Nguyen, Tuan Anh Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02860-1