The relationship between glucose and the liver-alpha cell axis – A systematic review

The relationship between glucose and the liver-alpha cell axis – A systematic review

Until recently, glucagon was considered a mere antagonist to insulin, protecting the body from hypoglycemia. This notion changed with the discovery of the liver-alpha cell axis (LACA) as a feedback loop. The LACA describes how glucagon secretion and pancreatic alpha cell proliferation are stimulated...

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Bibliographic Details
Main Authors: Thomas Pixner, Nathalie Stummer, Anna Maria Schneider, Andreas Lukas, Karin Gramlinger, Valérie Julian, David Thivel, Katharina Mörwald, Harald Mangge, Christopher Dalus, Elmar Aigner, Dieter Furthner, Daniel Weghuber, Katharina Maruszczak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
liver-alpha cell axis
glucagon
glucose
liver
OGTT
pediatric
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1061682/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1061682/full

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