The relationship between glucose and the liver-alpha cell axis – A systematic review

The relationship between glucose and the liver-alpha cell axis – A systematic review

Until recently, glucagon was considered a mere antagonist to insulin, protecting the body from hypoglycemia. This notion changed with the discovery of the liver-alpha cell axis (LACA) as a feedback loop. The LACA describes how glucagon secretion and pancreatic alpha cell proliferation are stimulated...

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Bibliographic Details
Main Authors:	Thomas Pixner, Nathalie Stummer, Anna Maria Schneider, Andreas Lukas, Karin Gramlinger, Valérie Julian, David Thivel, Katharina Mörwald, Harald Mangge, Christopher Dalus, Elmar Aigner, Dieter Furthner, Daniel Weghuber, Katharina Maruszczak
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Endocrinology
Subjects:	liver-alpha cell axis glucagon glucose liver OGTT pediatric
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1061682/full

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