Type 3 deiodinase: role in cancer growth, stemness and metabolism

Type 3 deiodinase: role in cancer growth, stemness and metabolism

Deiodinases are selenoenzymes that catalyze thyroid hormones (THs) activation (type 1 and type 2, D1 and D2 respectively) or inactivation (type 3, D3). THs are essential for proper body development and cellular differentiation. Their intra- and extra-cellular concentrations are tightly regulated by...

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Bibliographic Details
Main Authors: Domenico eCiavardelli, Maria eBellomo, Caterina eCrescimanno, Veronica eVella
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Endocrinology
Subjects:
deiodinase
Warburg effect
Stemness
D3
cancer stem cells (CSCs)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00215/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00215/full

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