Type 3 deiodinase: role in cancer growth, stemness and metabolism

Type 3 deiodinase: role in cancer growth, stemness and metabolism

Deiodinases are selenoenzymes that catalyze thyroid hormones (THs) activation (type 1 and type 2, D1 and D2 respectively) or inactivation (type 3, D3). THs are essential for proper body development and cellular differentiation. Their intra- and extra-cellular concentrations are tightly regulated by...

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Bibliographic Details
Main Authors:	Domenico eCiavardelli, Maria eBellomo, Caterina eCrescimanno, Veronica eVella
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-12-01
Series:	Frontiers in Endocrinology
Subjects:	deiodinase Warburg effect Stemness D3 cancer stem cells (CSCs)
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00215/full

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