M19 modulates skeletal muscle differentiation and insulin secretion in pancreatic β-cells through modulation of respiratory chain activity.

M19 modulates skeletal muscle differentiation and insulin secretion in pancreatic β-cells through modulation of respiratory chain activity.

Mitochondrial dysfunction due to nuclear or mitochondrial DNA alterations contributes to multiple diseases such as metabolic myopathies, neurodegenerative disorders, diabetes and cancer. Nevertheless, to date, only half of the estimated 1,500 mitochondrial proteins has been identified, and the funct...

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Bibliographic Details
Main Authors: Linda Cambier, Patrice Rassam, Béatrice Chabi, Karima Mezghenna, René Gross, Eric Eveno, Charles Auffray, Chantal Wrutniak-Cabello, Anne-Dominique Lajoix, Pascal Pomiès
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282743?pdf=render

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http://europepmc.org/articles/PMC3282743?pdf=render

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