Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures

Cell fate dynamics during human naïve pluripotency establishment remain poorly understood. Here, Bi et al. depict a high-resolution cell roadmap of the primed-to-naïve pluripotency transition, providing hints for embryo modeling-related studies.

Bibliographic Details
Main Authors: Yan Bi, Zhifen Tu, Jianfeng Zhou, Xuehao Zhu, Hong Wang, Shaorong Gao, Yixuan Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30924-1