Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures

Cell fate dynamics during human naïve pluripotency establishment remain poorly understood. Here, Bi et al. depict a high-resolution cell roadmap of the primed-to-naïve pluripotency transition, providing hints for embryo modeling-related studies.

Bibliographic Details
Main Authors: Yan Bi, Zhifen Tu, Jianfeng Zhou, Xuehao Zhu, Hong Wang, Shaorong Gao, Yixuan Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30924-1
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author Yan Bi
Zhifen Tu
Jianfeng Zhou
Xuehao Zhu
Hong Wang
Shaorong Gao
Yixuan Wang
author_facet Yan Bi
Zhifen Tu
Jianfeng Zhou
Xuehao Zhu
Hong Wang
Shaorong Gao
Yixuan Wang
author_sort Yan Bi
collection DOAJ
description Cell fate dynamics during human naïve pluripotency establishment remain poorly understood. Here, Bi et al. depict a high-resolution cell roadmap of the primed-to-naïve pluripotency transition, providing hints for embryo modeling-related studies.
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spelling doaj.art-12daf2032e584c91912a9d968aff21d82022-12-22T02:29:21ZengNature PortfolioNature Communications2041-17232022-06-0113111510.1038/s41467-022-30924-1Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signaturesYan Bi0Zhifen Tu1Jianfeng Zhou2Xuehao Zhu3Hong Wang4Shaorong Gao5Yixuan Wang6Shanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityShanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji UniversityCell fate dynamics during human naïve pluripotency establishment remain poorly understood. Here, Bi et al. depict a high-resolution cell roadmap of the primed-to-naïve pluripotency transition, providing hints for embryo modeling-related studies.https://doi.org/10.1038/s41467-022-30924-1
spellingShingle Yan Bi
Zhifen Tu
Jianfeng Zhou
Xuehao Zhu
Hong Wang
Shaorong Gao
Yixuan Wang
Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
Nature Communications
title Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
title_full Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
title_fullStr Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
title_full_unstemmed Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
title_short Cell fate roadmap of human primed-to-naive transition reveals preimplantation cell lineage signatures
title_sort cell fate roadmap of human primed to naive transition reveals preimplantation cell lineage signatures
url https://doi.org/10.1038/s41467-022-30924-1
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