Altered DNA methylation of CYP2E1 gene in schizophrenia patients with tardive dyskinesia

Altered DNA methylation of CYP2E1 gene in schizophrenia patients with tardive dyskinesia

Abstract Background About 20–30% of patients with schizophrenia develop tardive dyskinesia (TD). Oxidative stress is one potential causes of TD. CYP2E1 is considered as an oxidative stress-related gene, however, no study has been reported on the DNA methylation levels of the CYP2E1 in schizophrenia...

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Bibliographic Details
Main Authors: Ping Zhang, Yanli Li, Kesheng Wang, Junchao Huang, Brenda Bin Su, Chun Xu, Zhiren Wang, Shuping Tan, Fude Yang, Yunlong Tan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Medical Genomics
Subjects:
Schizophrenia
Tardive dyskinesia
Pyrosequencing
DNA methylation
CYP2E1
Oxidative stress
Online Access:https://doi.org/10.1186/s12920-022-01404-8

Internet

https://doi.org/10.1186/s12920-022-01404-8

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