Identification of a small‐molecule ligand of β‐arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells

Abstract Stromal fibroblasts, which occupy a major portion of the tumor microenvironment, play an important role in cancer metastasis. Thus, targeting of these fibroblasts activated by cancer cells (carcinoma‐associated fibroblasts; CAFs) might aid in the improved treatment of cancer metastasis. NIH...

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Bibliographic Details
Main Authors: Kruthi Suvarna, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Nobumoto Watanabe
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1339