Possible Involvement of Both Endoplasmic Reticulumand Mitochondria-Dependent Pathways in Thapsigargin-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells

Possible Involvement of Both Endoplasmic Reticulumand Mitochondria-Dependent Pathways in Thapsigargin-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells

Recently, it has been shown that endoplasmic reticulum (ER) stress causes apoptosis. However, the mechanism of the ER stress-dependent pathway is not fully understood. In human neuroblastoma SH-SY5Y cells, we detected a caspase-12-like protein that has a molecular mass (approximately 60 kDa) similar...

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Bibliographic Details
Main Authors: Yoshihisa Kitamura, Atsushi Miyamura, Kazuyuki Takata, Masatoshi Inden, Daiju Tsuchiya, Kumi Nakamura, Takashi Taniguchi
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326544

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http://www.sciencedirect.com/science/article/pii/S1347861319326544

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