miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway

miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway

MicroRNAs (miRNAs) are important regulators of stem and progenitor cell functions. We previously reported that miR-142 and miR-150 are upregulated in human breast cancer stem cells (BCSCs) as compared to the non-tumorigenic breast cancer cells. In this study, we report that miR-142 efficiently recru...

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Bibliographic Details
Main Authors: Taichi Isobe, Shigeo Hisamori, Daniel J Hogan, Maider Zabala, David G Hendrickson, Piero Dalerba, Shang Cai, Ferenc Scheeren, Angera H Kuo, Shaheen S Sikandar, Jessica S Lam, Dalong Qian, Frederick M Dirbas, George Somlo, Kaiqin Lao, Patrick O Brown, Michael F Clarke, Yohei Shimono
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-11-01
Series:eLife
Subjects:
breast cancer
cancer stem cell
miR-142
miR-150
APC
WNT signaling pathway
Online Access:https://elifesciences.org/articles/01977

Internet

https://elifesciences.org/articles/01977

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