Investigating the initial steps of auricin biosynthesis using synthetic biology

Investigating the initial steps of auricin biosynthesis using synthetic biology

Abstract Streptomyces lavendulae subsp. lavendulae CCM 3239 (formerly Streptomyces aureofaciens CCM 3239) contains a type II polyketide synthase (PKS) biosynthetic gene cluster (BGC) aur1 whose genes were highly similar to angucycline BGCs. However, its product auricin is structurally different from...

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Bibliographic Details
Main Authors: Dominika Csolleiova, Rachel Javorova, Renata Novakova, Lubomira Feckova, Maria Matulova, Filip Opaterny, Bronislava Rezuchova, Beatrica Sevcikova, Jan Kormanec
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:AMB Express
Subjects:
Antibiotics
Auricin
Biosynthetic gene cluster
Griseusin
Synthetic biology
Streptomyces
Online Access:https://doi.org/10.1186/s13568-023-01591-2

Internet

https://doi.org/10.1186/s13568-023-01591-2

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