Identification of a novel perifornical-hypothalamic-area-projecting serotonergic system that inhibits innate panic and conditioned fear responses

Abstract The serotonin (5-HT) system is heavily implicated in the regulation of anxiety and trauma-related disorders such as panic disorder and post-traumatic stress disorder, respectively. However, the neural mechanisms of how serotonergic neurotransmission regulates innate panic and fear brain net...

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Bibliographic Details
Main Authors: Cristian S. Bernabe, Izabela F. Caliman, Aline R. R. de Abreu, Andrei I. Molosh, William A. Truitt, Anantha Shekhar, Philip L. Johnson
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02769-3