Towards an arthritis flare-responsive drug delivery system

Towards an arthritis flare-responsive drug delivery system

The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.

Bibliographic Details
Main Authors: Nitin Joshi, Jing Yan, Seth Levy, Sachin Bhagchandani, Kai V. Slaughter, Nicholas E. Sherman, Julian Amirault, Yufeng Wang, Logan Riegel, Xueyin He, Tan Shi Rui, Michael Valic, Praveen K. Vemula, Oscar R. Miranda, Oren Levy, Ellen M. Gravallese, Antonios O. Aliprantis, Joerg Ermann, Jeffrey M. Karp
Format: Article
Language:English
Published: Nature Portfolio 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03691-1

Internet

https://doi.org/10.1038/s41467-018-03691-1

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