Immunosuppressant exposure confounds gene expression analysis in systemic lupus erythematosus

Immunosuppressant exposure confounds gene expression analysis in systemic lupus erythematosus

ObjectivesThe analysis of gene module expression in SLE is emerging as a tool to identify active biological pathways, with the aim of developing targeted therapies for subsets of patients. Detailed information on the effect of immunosuppressants on gene module expression is lacking. We aimed to exam...

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Bibliographic Details
Main Authors: Melissa Northcott, Linden J. Gearing, Julie Bonin, Rachel Koelmeyer, Alberta Hoi, Paul J. Hertzog, Eric F. Morand
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
transcriptional profiling
gene modules
immunosuppressants
glucocorticoids
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.964263/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.964263/full

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