Attenuating RNA Viruses with Expanded Genetic Codes to Evoke Adjustable Immune Response in PylRS-<inline-formula><math display="inline"><semantics><msubsup><mrow><mi mathvariant="bold">tRNA</mi></mrow><mrow><mi mathvariant="bold">CUA</mi></mrow><mrow><mi mathvariant="bold">Pyl</mi></mrow></msubsup></semantics></math></inline-formula> Transgenic Mice
Ribonucleic acid (RNA) viruses pose heavy burdens on public-health systems. Synthetic biology holds great potential for artificially controlling their replication, a strategy that could be used to attenuate infectious viruses but is still in the exploratory stage. Herein, we used the genetic-code ex...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/11/10/1606 |