Heparanase—A Link between Coagulation, Angiogenesis, and Cancer

Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner. Heparanase was shown to up-regulate tissue factor (TF) ex...

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Bibliographic Details
Main Authors: Yona Nadir, Benjamin Brenner
Format: Article
Language:English
Published: Rambam Health Care Campus 2012-01-01
Series:Rambam Maimonides Medical Journal
Subjects:
Online Access:http://rmmj.org.il/(S(qbrl5xa0ajlceycifuwzrvnh))/Pages/ArticleHTM.aspx?manuId=146