Qing`e Pill Inhibits Osteoblast Ferroptosis via ATM Serine/Threonine Kinase (ATM) and the PI3K/AKT Pathway in Primary Osteoporosis

Qing`e Pill Inhibits Osteoblast Ferroptosis via ATM Serine/Threonine Kinase (ATM) and the PI3K/AKT Pathway in Primary Osteoporosis

Osteoporosis (OP) is an aging-related disease that is the main etiology of fragility fracture. Qing’e Pill (QEP) is a mixture of traditional Chinese medicine (TCM) consisting of Eucommia ulmoides Oliv., Psoralea corylifolia L., Juglans regia L., and Allium sativum L. QEP has an anti-osteoporosis fun...

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Bibliographic Details
Main Authors: Jian Hao, Jiaxin Bei, Zhenhan Li, Mingyuan Han, Boyuan Ma, Pengyi Ma, Xianhu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
osteoporosis
PI3K/AKT pathway
ATM
ferroptosis
network analysis
Qing'e Pill
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.902102/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.902102/full

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