Cellular location shapes quaternary structure of enzymes

Abstract The main forces driving protein complex evolution are currently not well understood, especially in homomers, where quaternary structure might frequently evolve neutrally. Here we examine the factors determining oligomerisation by analysing the evolution of enzymes in circumstances where hom...

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Bibliographic Details
Main Authors: György Abrusán, Aleksej Zelezniak
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52662-2