APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.

APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.

The hallmarks of Alzheimer's disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of hippocampal neurons accompanied by a decline in...

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Main Authors: Melanie Laßek, Jens Weingarten, Martin Wegner, Benjamin F Mueller, Marion Rohmer, Dominic Baeumlisberger, Tabiwang N Arrey, Meike Hick, Jörg Ackermann, Amparo Acker-Palmer, Ina Koch, Ulrike Müller, Michael Karas, Walter Volknandt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4836664?pdf=render

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http://europepmc.org/articles/PMC4836664?pdf=render

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