Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells

Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells

Novel therapeutics are urgently needed to prevent opportunistic infections in immunocompromised individuals undergoing cancer treatments or other immune-suppressive therapies. Trained immunity is a promising strategy to reduce this burden of disease. We previously demonstrated that mesenchymal strom...

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Bibliographic Details
Main Authors: Julie Ng, Anna E. Marneth, Alec Griffith, Daniel Younger, Sailaja Ghanta, Alan Jiao, Gareth Willis, Junwen Han, Jewel Imani, Bailin Niu, Joshua W. Keegan, Brandon Hancock, Fei Guo, Yang Shi, Mark A. Perrella, James A. Lederer
Format: Article
Language:English
Published: Karger Publishers 2023-10-01
Series:Journal of Innate Immunity
Subjects:
trained immunity
epigenetics
hematopoietic stem cells
neutrophils
toll-like receptor 9
Online Access:https://beta.karger.com/Article/FullText/533732

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https://beta.karger.com/Article/FullText/533732

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