5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical information

5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical information

Abstract Background Colorectal cancer is a commonly diagnosed cancer worldwide. Unfortunately, many patients do not respond to standard chemotherapy treatments and develop disease relapse and metastases. Besides cancer cell specific genetic changes, heterogeneity in the tumor microenvironment contri...

Full description

Bibliographic Details
Main Authors: Simona Salerno, Anders Ståhlberg, André Holdfeldt, Elinor Bexe Lindskog, Göran Landberg
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Patient-derived scaffold
Decellularized matrix
5-fluorouracil
Drug screening
Online Access:https://doi.org/10.1186/s12967-022-03423-6

Internet

https://doi.org/10.1186/s12967-022-03423-6

Similar Items