Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry

Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry

Abstract Background Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder with a substantial genetic component. However, the clinical manifestations of PCOS are heterogeneous with notable differences between lean and obese women, implying a different pathophysiology manifesting in di...

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Bibliographic Details
Main Authors: Kharis Burns, Benjamin H. Mullin, Loes M. E. Moolhuijsen, Triin Laisk, Jaakko S. Tyrmi, Jinrui Cui, Ky’Era V. Actkins, Yvonne V. Louwers, Estonian Biobank Research Team, Lea K. Davis, Frank Dudbridge, Ricardo Azziz, Mark O. Goodarzi, Hannele Laivuori, Reedik Mägi, Jenny A. Visser, Joop S. E. Laven, Scott G. Wilson, FinnGen, International PCOS Consortium, Felix R. Day, Bronwyn G. A. Stuckey
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Genomics
Subjects:
Polycystic ovary syndrome
PCOS
GWAS
Meta-analysis
Lean
Obese
Online Access:https://doi.org/10.1186/s12864-024-09990-w

Internet

https://doi.org/10.1186/s12864-024-09990-w

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