SLCO1B1 and CYP3A4 allelic variants associated with pharmacokinetic interactions and adverse reactions induced by simvastatin and atorvastatin used in Peru: Clinical implications

SLCO1B1 and CYP3A4 allelic variants associated with pharmacokinetic interactions and adverse reactions induced by simvastatin and atorvastatin used in Peru: Clinical implications

Context: Statins reduce the risk of stroke and prevent cardiac events in people with atherosclerosis and diabetes mellitus; and could affect the proliferation, migration, and survival of cancer cells. Aims: To review the most up-to-date and available scientific evidence on the allelic variants of...

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Main Authors: Angel T. Alvarado, Ana María Muñoz, Roberto O. Ybañez-Julca, Mario Pineda-Pérez, Nesquen Tasayco-Yataco, María R. Bendezú, Jorge A. García, Felipe Surco-Laos, Haydee Chávez, Doris Laos-Anchante, Aura Molina-Cabrera, Carmela Ferreyra-Paredes, Nelly Vega-Ramos, Patricia Castillo-Romero, Javier Chávez-Espinoza, Juan Panay-Centeno, Eliades Yarasca-Carlos
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2023-11-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
adverse reactions
atorvastatin
cyp3a4
pharmacokinetic interactions
slco1b1
simvastatin
Online Access:https://jppres.com/jppres/pdf/vol11/jppres23.1686_11.6.934.pdf

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https://jppres.com/jppres/pdf/vol11/jppres23.1686_11.6.934.pdf

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