Paradoxical role of high mobility group box 1 in glioma: a suppressor or a promoter?

Gliomas represent 60% of primary intracranial brain tumors and 80% of all malignant types, with highest morbidity and mortality worldwide. Although glioma has been extensively studied, the molecular mechanisms underlying its pathology remain poorly understood. Clarification of the molecular mechanis...

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Bibliographic Details
Main Authors: Richard A. Seidu, Min Wu, Zhaoliang Su, Huaxi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-03-01
Series:Oncology Reviews
Subjects:
Online Access:http://www.oncologyreviews.org/index.php/or/article/view/325