A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci

A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci

PyFoci is a tool that simulates distributions of fluorescently labeled DNA double-strand break marker protein foci and allows the estimation of miscounting under different radiation types, doses and microscopy settings.

Bibliographic Details
Main Authors: Samuel P. Ingram, John-William Warmenhoven, Nicholas T. Henthorn, Amy L. Chadiwck, Elham E. Santina, Stephen J. McMahon, Jan Schuemann, Norman F. Kirkby, Ranald I. Mackay, Karen J. Kirkby, Michael J. Merchant
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03585-5

Internet

https://doi.org/10.1038/s42003-022-03585-5

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