Sensitive Immunofluorescent Detection of the PRAME Antigen Using a Practical Antibody Conjugation Approach

Sensitive Immunofluorescent Detection of the PRAME Antigen Using a Practical Antibody Conjugation Approach

Bioconjugation of antibodies with various payloads has diverse applications across various fields, including drug delivery and targeted imaging techniques. Fluorescent immunoconjugates provide a promising tool for cancer diagnostics due to their high brightness, specificity, stability and target aff...

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Bibliographic Details
Main Authors: Ksenia A. Sapozhnikova, Vsevolod A. Misyurin, Dmitry Y. Ryazantsev, Egor A. Kokin, Yulia P. Finashutina, Anastasiya V. Alexeeva, Igor A. Ivanov, Milita V. Kocharovskaya, Nataliya A. Tikhonova, Galina P. Popova, Vera A. Alferova, Alexey V. Ustinov, Vladimir A. Korshun, Vladimir A. Brylev
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
antibodies
PRAME
oxime ligation
ethoxyethylidene protecting group
fluorescent dyes
fluorescence imaging
Online Access:https://www.mdpi.com/1422-0067/22/23/12845

Internet

https://www.mdpi.com/1422-0067/22/23/12845

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