Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease.

Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease.

Chagas disease, caused by Trypanosoma cruzi, is endemic in Latin America and an emerging infectious disease in the US and Europe. We have shown TcG1, TcG2, and TcG4 antigens elicit protective immunity to T. cruzi in mice and dogs. Herein, we investigated antigenicity of the recombinant proteins in h...

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Bibliographic Details
Main Authors: Shivali Gupta, Xianxiu Wan, Maria P Zago, Valena C Martinez Sellers, Trevor S Silva, Dadjah Assiah, Monisha Dhiman, Sonia Nuñez, John R Petersen, Juan C Vázquez-Chagoyán, Jose G Estrada-Franco, Nisha Jain Garg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3547861?pdf=render

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http://europepmc.org/articles/PMC3547861?pdf=render

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