Heritability of Low ER Staining/HER2-Breast Tumors: Are We Missing an Opportunity for Germline Testing?

In 2010, the genetic testing criteria was changed to allow women diagnosed ≤ 60 years old with triple negative breast cancer (TNBC) to undergo germline testing. In the same year, estrogen receptor (ER) positivity was defined as having ≥1% ER staining cells. While tumors with 1–10% ER staining cells...

Full description

Bibliographic Details
Main Authors: Leann A. Lovejoy, Clesson E. Turner, Justin M. Wells, Craig D. Shriver, Rachel E. Ellsworth
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/12/1469