Identifying stem cell numbers and functional heterogeneities during postembryonic organ growth
Summary: Uncovering the number of stem cells necessary for organ growth has been challenging in vertebrate systems. Here, we developed a mathematical model characterizing stem cells in the fish gill, an organ displaying non-exhaustive growth. We employ a Markov model, stochastically simulated via an...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-02-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422200089X |