A novel stability-indicating chromatographic quantification of the antiparkinsonian drug safinamide in its pharmaceutical formulation employing HPTLC densitometry and ion-pair HPLC–DAD

A novel stability-indicating chromatographic quantification of the antiparkinsonian drug safinamide in its pharmaceutical formulation employing HPTLC densitometry and ion-pair HPLC–DAD

Abstract Parkinson's disease (PD) emerges as a notable health concern among the elderly population. Safinamide mesylate (SAF) is a novel and emerging add-on therapy in PD treatment. The stability of innovative drug formulations and the development of appropriate stability-indicating methods are...

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Bibliographic Details
Main Authors: Engy A. Ibrahim, Samah S. Saad, Maha A. Hegazy, Laila E. Abdel Fattah, Hoda M. Marzouk
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Chemistry
Subjects:
HPTLC-densitometry
HPLC–DAD
In-vitro release
Safinamide Mesylate
Stability indicating methods
4-hydroxy benzaldehyde
Online Access:https://doi.org/10.1186/s13065-024-01315-y

Internet

https://doi.org/10.1186/s13065-024-01315-y

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