Characterizing replisome disassembly in human cells

Summary: To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on genomic DNA at any time during S phase. In the final stages of this process, replisomes are unloaded from chromatin. Unloading is driven by polyubiquitylation of MCM7, a su...

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Библиографические подробности
Главные авторы: Rebecca M. Jones, Joaquin Herrero Ruiz, Shaun Scaramuzza, Sarmi Nath, Chaoyu Liu, Marta Henklewska, Toyoaki Natsume, Robert G. Bristow, Francisco Romero, Masato T. Kanemaki, Agnieszka Gambus
Формат: Статья
Язык:English
Опубликовано: Elsevier 2024-07-01
Серии:iScience
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Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2589004224014858