Characterizing replisome disassembly in human cells
Summary: To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on genomic DNA at any time during S phase. In the final stages of this process, replisomes are unloaded from chromatin. Unloading is driven by polyubiquitylation of MCM7, a su...
Главные авторы: | , , , , , , , , , , |
---|---|
Формат: | Статья |
Язык: | English |
Опубликовано: |
Elsevier
2024-07-01
|
Серии: | iScience |
Предметы: | |
Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2589004224014858 |