PROT-ON: A structure-based detection of designer PROTein interface MutatiONs

The mutation-induced changes across protein-protein interfaces have often been observed to lead to severe diseases. Therefore, several computational tools have been developed to predict the impact of such mutations. Among these tools, FoldX and EvoEF1 stand out as fast and accurate alternatives. Exp...

Full description

Bibliographic Details
Main Authors: Mehdi Koşaca, İrem Yılmazbilek, Ezgi Karaca
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1063971/full